Article
Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.
Infection and immunity - 1 Feb 1997
Fleiszig S M, Wiener-Kronish J P, Miyazaki H, Vallas V, Mostov K E, Kanada D, Sawa T, Yen T S, Frank D W
Abstract excerpt
Pseudomonas aeruginosa, an opportunistic pathogen, is capable of establishing both chronic and acute infections in compromised hosts. Previous studies indicated that P. aeruginosa displays either a cytotoxic or an invasive phenotype in corneal epithelial cells. In this study, we used polarized MD...
Topics
- ADP Ribose Transferases
- Animals
- Bacterial Toxins
- Blotting, Southern
- Cell Line
- Cell Polarity
- Cytotoxicity, Immunologic
- DNA, Bacterial
- Dogs
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Genotype
- Kidney
- Mutation