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Article

The role of HLA-B27 in spondyloarthritis.

Immunogenetics - 1 Nov 1999

Allen R L, Bowness P, McMichael A

Abstract excerpt

The human major histocompatibility complex (MHC) class I allele HLA-B27 bears a striking association with the spondylolarthritic group of inflammatory arthritides, yet despite extensive studies its role in the disease process remains obscure. As an MHC class I protein, the primary function of HLA-B27 is to complex with beta(2)-microglobulin forming a structure that presents short antigenic peptides for...

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Source

Identifiers

PMID: 10602882
DOI: 10.1007/s002510050596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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