Article
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
The Journal of cell biology - 13 Dec 1999
Gimond C, van Der Flier A, van Delft S, Brakebusch C, Kuikman I, Collard J G, Fässler R, Sonnenberg A
Abstract excerpt
Adhesion receptors, which connect cells to each other and to the surrounding extracellular matrix (ECM), play a crucial role in the control of tissue structure and of morphogenesis. In this work, we have studied how intercellular adhesion molecules and beta1 integrins influence each other using two different beta1-null cell lines, epithelial GE11 and fibroblast-like GD25 cells. Expression of beta1A or the...
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