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Article

A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila.

PLoS genetics - 1 Nov 2008

Cauchi Ruben J, Davies Kay E, Liu Ji-Long

Abstract excerpt

The survival motor neuron (SMN) protein, the determining factor for spinal muscular atrophy (SMA), is complexed with a group of proteins in human cells. Gemin3 is the only RNA helicase in the SMN complex. Here, we report the identification of Drosophila melanogaster Gemin3 and investigate its function in vivo. Like in vertebrates, Gemin3 physically interacts with SMN in Drosophila. Loss of function of gemin3...

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Source

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Identifiers

PMID: 19023405
DOI: 10.1371/journal.pgen.1000265
PMCID: PMC2577925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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