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Article

SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin.

The EMBO journal - 15 Dec 1999

Sekinger E A, Gross D S

Abstract excerpt

Previous work has suggested that products of the Saccharomyces cerevisiae Silent Information Regulator (SIR) genes form a complex with histones, nucleated by cis-acting silencers or telomeres, which represses transcription in a position-dependent but sequence-independent fashion. While it is generally thought that this Sir complex works through the establishment of heterochromatin, it is unclear how this...

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Identifiers

PMID: 10601026
DOI: 10.1093/emboj/18.24.7041
PMCID: PMC1171767

Genes

TBP

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Source receipt: pubmed, retrieved 7 Sept 2026.

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SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin.PMID 10601026Read ↗

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