SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin.

doi:10.1093/emboj/18.24.7041

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Article

SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin.

The EMBO journal - 15 Dec 1999

Sekinger E A, Gross D S

Abstract excerpt

Previous work has suggested that products of the Saccharomyces cerevisiae Silent Information Regulator (SIR) genes form a complex with histones, nucleated by cis-acting silencers or telomeres, which represses transcription in a position-dependent but sequence-independent fashion. While it is generally thought that this Sir complex works through the establishment of heterochromatin, it is unclear how this...

Topics

Binding Sites
DNA Footprinting
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins
Gene Silencing
Genes, Fungal
Genes, Mating Type, Fungal
Genotype
HSP90 Heat-Shock Proteins
Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterochromatin

Histones

Promoter Regions, Genetic

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

TATA Box

Telomere

Source

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Identifiers

PMID: 10601026
DOI: 10.1093/emboj/18.24.7041
PMCID: PMC1171767

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