Article
Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90.
Biochemical Society transactions - 19 Feb 2018
Mazaira Gisela I, Daneri-Becerra Cristina, Zgajnar Nadia R, Lotufo Cecilia M, Galigniana Mario D
Abstract excerpt
The ability to permit gene expression is managed by a set of relatively well known regulatory mechanisms. Nonetheless, this property can also be acquired during a life span as a consequence of environmental stimuli. Interestingly, some acquired information can be passed to the next generation of individuals without modifying gene information, but instead by the manner in which cells read and process such...
Topics
- Animals
- Gene Expression Regulation
- Genetic Variation
- HSP90 Heat-Shock Proteins
- Heat Shock Transcription Factors
- Histone Deacetylase 6
- Humans
- Protein Folding
- Protein Processing, Post-Translational
- Stress, Physiological