Article
Cell cycle-dependent binding of yeast heat shock factor to nucleosomes.
Molecular and cellular biology - 1 Sept 2000
Venturi C B, Erkine A M, Gross D S
Abstract excerpt
In the nucleus, transcription factors must contend with the presence of chromatin in order to gain access to their cognate regulatory sequences. As most nuclear DNA is assembled into nucleosomes, activators must either invade a stable, preassembled nucleosome or preempt the formation of nucleosomes on newly replicated DNA, which is transiently free of histones. We have investigated the mechanism by which heat...
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