Article
Remarkable site specificity of local transposition into the Hsp70 promoter of Drosophila melanogaster.
Genetics - 1 Jun 2006
Shilova Victoria Y, Garbuz David G, Myasyankina Elena N, Chen Bing, Evgen'ev Michael B, Feder Martin E, Zatsepina Olga G
Abstract excerpt
Heat-shock genes have numerous features that ought to predispose them to insertional mutagenesis via transposition. To elucidate the evolvability of heat-shock genes via transposition, we have exploited a local transposition technique and Drosophila melanogaster strains with EPgy2 insertions near the Hsp70 gene cluster at 87A7 to produce numerous novel EPgy2 insertions into these Hsp70 genes. More than 50% of 45...
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