Article
CTLA-4 +49 A/G dimorphism in Italian patients with celiac disease.
Human immunology - 1 Feb 2003
Mora Barbara, Bonamico Margherita, Indovina Paola, Megiorni Francesca, Ferri Mirella, Carbone Maria C, Cipolletta Elsa, Mazzilli Maria C
Abstract excerpt
The chromosome region 2q33, which contains the cytotoxic T lymphocyte antigen-4 (CTLA-4) gene, has been reported in linkage and association with celiac disease (CD). In the present work we have tested the association between the polymorphism of the CTLA-4 exon 1 and susceptibility to CD in an Italian population, using case-control and family-based approaches. The +49 A/G dimorphism was analyzed in 86 patients,...
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