Article
Systematic search for disease loci for complex genetic traits: a study based on simulated population data.
Genetic epidemiology - 1 Jan 1999
Falk C T
Abstract excerpt
Simulated family data were analyzed using one- and two-locus disease models to detect linkage. Regions of interest, found on chromosomes 3 and 5, were then further analyzed to look for evidence of locus interaction and/or genetic heterogeneity. Methods described by Falk [1993] were used to separate families into subsets likely to be genetically homogeneous. Based on the results, it was concluded that there were...
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