Article
The NADH oxidase of Streptococcus pneumoniae: its involvement in competence and virulence.
Molecular microbiology - 1 Dec 1999
Auzat I, Chapuy-Regaud S, Le Bras G, Dos Santos D, Ogunniyi A D, Le Thomas I, Garel J R, Paton J C, Trombe M C
Abstract excerpt
A soluble flavoprotein that reoxidizes NADH and reduces molecular oxygen to water was purified from the facultative anaerobic human pathogen Streptococcus pneumoniae. The nucleotide sequence of nox, the gene which encodes it, has been determined and was characterized at the functional and physiological level. Several nox mutants were obtained by insertion, nonsense or missense mutation. In extracts from these...
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