Article
Contribution of NADH oxidase to aerobic metabolism of Streptococcus pyogenes.
Journal of bacteriology - 1 Jan 2000
Gibson C M, Mallett T C, Claiborne A, Caparon M G
Abstract excerpt
An understanding of how the heme-deficient gram-positive bacterium Streptococcus pyogenes establishes infections in O(2)-rich environments requires careful analysis of the gene products important in aerobic metabolism. NADH oxidase (NOXase) is a unique flavoprotein of S. pyogenes and other lactic acid bacteria which directly catalyzes the four-electron reduction of O(2) to H(2)O. To elucidate a putative role for...
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