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Article

Mutation of the NADH oxidase gene (nox) reveals an overlap of the oxygen- and acid-mediated stress responses in Streptococcus mutans.

Applied and environmental microbiology - 1 Feb 2012

Derr Adam M, Faustoferri Roberta C, Betzenhauser Matthew J, Gonzalez Kaisha, Marquis Robert E, Quivey Robert G

Abstract excerpt

NADH oxidase (Nox) is a flavin-containing enzyme used by Streptococcus mutans to reduce dissolved oxygen encountered during growth in the oral cavity. In this study, we characterized the role of the NADH oxidase in the oxidative and acid stress responses of S. mutans. A nox-defective mutant strain of S. mutans and its parental strain, the genomic type strain UA159, were exposed to various oxygen concentrations at...

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Identifiers

PMID: 22179247
DOI: 10.1128/AEM.06890-11
PMCID: PMC3273017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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