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Article

The Staphylococcus aureus SrrAB two-component system promotes resistance to nitrosative stress and hypoxia.

mBio - 12 Nov 2013

Kinkel Traci L, Roux Christelle M, Dunman Paul M, Fang Ferric C

Abstract excerpt

UNLABELLED: Staphylococcus aureus is both a commensal and a pathogen of the human host. Survival in the host environment requires resistance to host-derived nitric oxide (NO·). However, S. aureus lacks the NO·-sensing transcriptional regulator NsrR that is used by many bacteria to sense and respond to NO·. In this study, we show that S. aureus is able to sense and respond to both NO· and hypoxia by means of the...

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Source

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Identifiers

PMID: 24222487
DOI: 10.1128/mBio.00696-13
PMCID: PMC3892780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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