Article
Competence regulation by oxygen in Streptococcus pneumoniae: involvement of ciaRH and comCDE.
Molecular microbiology - 1 May 2000
Echenique J R, Chapuy-Regaud S, Trombe M C
Abstract excerpt
Anaerobic aerotolerant Streptococcus pneumoniae modulates its genetic transformability and its virulence in response to the oxygen concentration. The activity of a single protein encoded by nox and showing NADH oxidase activity is involved in these adaptive responses to O2. Northern blot analysis of wild-type cultures grown under aerobic and microaerobic conditions indicated transcriptional control of comCDE by...
Topics
- Anaerobiosis
- Bacterial Proteins
- Gene Expression Regulation, Bacterial
- Genotype
- Histidine Kinase
- Multienzyme Complexes
- Mutagenesis
- Oxygen
- Phenotype
- Point Mutation
- Protein Kinases
- Streptococcus pneumoniae
- Transcription, Genetic
- Transformation, Bacterial
- Virulence
