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The Group B Streptococcus NADH oxidase Nox-2 is involved in fatty acid biosynthesis during aerobic growth and contributes to virulence.

Molecular microbiology - 1 Nov 2006

Yamamoto Yuji, Pargade Vincent, Lamberet Gilles, Gaudu Philippe, Thomas Fabrice, Texereau Joelle, Gruss Alexandra, Trieu-Cuot Patrick, Poyart Claire

Abstract excerpt

Numerous Streptococcaceae produce an H2O-forming NADH oxidase, Nox-2, which has been generally implicated in aerobic survival. We examined the roles of Nox-2 in Group B Streptococcus (GBS), a leading agent of neonatal infections. While nox2 inactivation caused an aerobic growth arrest, no improvement was seen by addition of antioxidants to cultures, suggesting that this defect was not due to accumulation of toxic...

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PMID: 16999835
DOI: 10.1111/j.1365-2958.2006.05406.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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