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Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection.

Microbiology (Reading, England) - 1 Feb 2001

Yu Jun, Bryant Alexander P, Marra Andrea, Lonetto Michael A, Ingraham Karen A, Chalker Alison F, Holmes David J, Holden David, Rosenberg Martin, McDevitt Damien

Abstract excerpt

Streptococcus pneumoniae is an important human pathogen capable of causing serious infections. NADH oxidase, a factor necessary for infection, was previously identified as part of a signature-tagged mutagenesis screen of a S. pneumoniae clinical isolate, 0100993. The mutant, with a plasmid insertion disrupting the nox gene, was attenuated for virulence in a murine respiratory tract infection model. A complete...

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PMID: 11158360
DOI: 10.1099/00221287-147-2-431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection.PMID 11158360Read ↗

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