Article
Characterization of a candidate <i>Borrelia burgdorferi</i>β<sub>3</sub>‐chain integrin ligand identified using a phage display library
1 Dec 1999
Abstract excerpt
The spirochaetal agents of Lyme disease, Borrelia burgdorferi (sensu lato) bind to integrins alphaIIbbeta3, alphavbeta3 and alpha5beta1 in purified form and on the surfaces of human cells. Using a phage display library of B. burgdorferi (sensu stricto) DNA, a candidate ligand for beta3-chain integrins was identified. The native B. burgdorferi protein, termed p66, is known to be recognized by human Lyme disease...
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