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Article

The BBA 33 lipoprotein binds collagen and impacts B orrelia burgdorferi pathogenesis

6 Jan 2015

Abstract excerpt

Borrelia burgdorferi, the etiologic agent of Lyme disease, adapts to the mammalian hosts by differentially expressing several genes in the BosR and Rrp2-RpoN-RpoS dependent pathways, resulting in a distinct protein profile relative to that seen for survival in the Ixodes spp. tick. Previous studies indicate that a putative lipoprotein, BBA33, is produced in an RpoS-dependent manner under conditions that mimic the...

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PMID: 25560615
DOI: 10.1111/mmi.12921

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