Back to search

Article

Exploring Outer Surface Protein A from <em>Borrelia afzelii</em>: Cloning, Expression, and Characterization for Zoonotic Disease Research

2024-11-28

Abstract excerpt

Lyme disease (LD), caused by Borrelia burgdorferi sensu lato, is transmitted through the bite of infected ticks. Outer surface protein A (OspA) is a major lipoprotein expressed by Borrelia species, playing a critical role in the colonization of the tick midgut. OspA is a key target in diagnostic and vaccine development due to its conserved nature across Borrelia species. This study focuses on the expression and ch...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
17e1f121-dddf-56a3-b6df-b83f015293c3
DOI
10.20944/preprints202411.2231.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Exploring Outer Surface Protein A from <em>Borrelia afzelii</em>: Cloning, Expression, and Characterization for Zoonotic Disease ResearchDOI 10.20944/preprints202411.2231.v1
Characterization of the inner membrane protein BB0173 from Borrelia burgdorferi.Semantic proximity
Development of a sequence-based <i>in silico</i> OspA typing method for <i>Borrelia burgdorferi</i> sensu latoSemantic proximity
The role of Borrelia burgdorferi outer surface proteinsSemantic proximity
Recent discoveries and advancements in research on the Lyme disease spirochete Borrelia burgdorferiSemantic proximity
<i>Borrelia</i>Outer Membrane Surface Proteins and Transmission Through the TickSemantic proximity
<i>Borrelia Burgdorferi</i> and Tick Proteins Supporting Pathogen Persistence in the VectorSemantic proximity
Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial SurfaceSemantic proximity
That's my story, and I'm sticking to it—an update on B. burgdorferi adhesinsSemantic proximity
Illuminating the roles of the Borrelia burgdorferi adhesinsSemantic proximity
Improvement the expression and purification of Loa22: a lipoprotein with OmpA domain from pathogenic Leptospira serovarsSemantic proximity
The need to unravel the twisted nature of the Borrelia burgdorferi sensu lato complex across Europe.Semantic proximity
Characterization of Multiprotein Complexes of the <i>Borrelia burgdorferi</i> Outer Membrane VesiclesSemantic proximity
Select a neighboring publication to make it the new centre.