Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A human secretome library screen reveals a role for Peptidoglycan Recognition Protein 1 in Lyme borreliosis

11 Nov 2020

Abstract excerpt

Lyme disease, the most common vector-borne illness in North America, is caused by the spirochete Borrelia burgdorferi. Infection begins in the skin following a tick bite and can spread to the hearts, joints, nervous system, and other organs. Diverse host responses influence the level of B. burgdorferi infection in mice and humans. Using a systems biology approach, we examined potential molecular interactions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect and Pesticide Research
Share to Vector-borne infectious diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33175909
DOI: 10.1371/journal.ppat.1009030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A human secretome library screen reveals a role for Peptidoglycan Recognition Protein 1 in Lyme borreliosisPMID 33175909Read ↗

Molecular Interactions that Enable Movement of the Lyme Disease Agent from the Tick Gut into the HemolymphSemantic proximity Read ↗

Bacterial and host enzymes modulate the inflammatory response produced by the peptidoglycan of the Lyme disease agentSemantic proximity Read ↗

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.Semantic proximity Read ↗

Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial SurfaceSemantic proximity Read ↗

Lipoproteome screening of the Lyme disease agent identifies novel inhibitors of antibody-mediated complement killingSemantic proximity Read ↗

Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis.Semantic proximity Read ↗

Detection of cytosolic <i>Shigella flexneri</i> via a C-terminal triple-arginine motif of GBP1 inhibits actin-based motilitySemantic proximity Read ↗

Lyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infectionSemantic proximity Read ↗

A Genome-Wide Proteome Array Reveals a Limited Set of Immunogens in Natural Infections of Humans and White-Footed Mice with<i>Borrelia burgdorferi</i>Semantic proximity Read ↗

A dual role for PGLYRP1 in host defense and immune regulation during <i>B. pertussis</i> infectionSemantic proximity Read ↗

Human genetic variation reveals FCRL3 is a lymphocyte receptor for <i>Yersinia pestis</i>Semantic proximity Read ↗

Borrelia PeptideAtlas: A proteome resource of common <i>Borrelia burgdorferi</i> isolates for Lyme researchSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.