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<i>Borrelia burgdorferi</i> adhesins identified using <i>in vivo</i> phage display

28 Aug 2007

Abstract excerpt

Borrelia burgdorferi, the agent of Lyme disease, disseminates from the site of deposition by Ixodes ticks to cause systemic infection. Dissemination occurs through the circulation and through tissue matrices, but the B. burgdorferi molecules that mediate interactions with the endothelium in vivo have not yet been identified. In vivo selection of filamentous phage expressing B. burgdorferi protein fragments on the...

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PMID: 17784908
DOI: 10.1111/j.1365-2958.2007.05924.x

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