Article
A Novel Laminin-Binding Protein Mediates Microbial-Endothelial Cell Interactions and Facilitates Dissemination of Lyme Disease Pathogens.
The Journal of infectious diseases - 7 Apr 2020
Bista Sandhya, Singh Preeti, Bernard Quentin, Yang Xiuli, Hart Thomas, Lin Yi-Pin, Kitsou Chrysoula, Singh Rana Vipin, Zhang Fuming, Linhardt Robert J, Zhnag Kai, Akins Darrin R, Hritzo Lucy, Kim Yuri, Grab Dennis J, Dumler J Stephen, Pal Utpal
Abstract excerpt
Borrelia burgdorferi conserved gene products BB0406 and BB0405, members of a common B. burgdorferi paralogous gene family, share 59% similarity. Although both gene products can function as potential porins, only BB0405 is essential for infection. Here we show that, despite sequence homology and coexpression from the same operon, both proteins differ in their membrane localization attributes, antibody...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.