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Article

<i>Pax6</i> is essential for establishing ventral-dorsal cell boundaries in pituitary gland development

7 Dec 1999

Abstract excerpt

Pax6, a highly conserved member of the paired homeodomain transcription factor family that plays essential roles in ocular, neural, and pancreatic development and effects asymmetric transient dorsal expression during pituitary development, with its expression extinguished before the ventral --> dorsal appearance of specific cell types. Analysis of pituitary development in the Small eye and Pax6 -/- mouse mutants...

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PMID: 10588713
DOI: 10.1073/pnas.96.25.14378

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