Article

Increased TSH-producing cells in the pituitary gland of Pax6 haploinsufficient mice

2020-04-07

Abstract excerpt

Aniridia is a congenital condition characterized by absence of iris and is caused by a semidominant mutation in the transcription factor encoded by the PAX6 gene. Although ocular phenotypes of this disorder are well characterized, recent studies report that individuals with aniridia have a higher propensity for obesity, infertility, polycystic ovarian disease, and severe eczema compared to their Pax6 -normal sib...

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Literature Corpus work: b269add6-7261-54e0-baf9-a2a2531be811
DOI: 10.1101/2020.04.06.028282

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