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Article

Increased HLA class II risk is associated with a more aggressive presentation of clinical type 1 diabetes.

Acta paediatrica (Oslo, Norway : 1992) - 1 Mar 2023

Kieleväinen Vilma, Turtinen Maaret, Luopajärvi Kristiina, Härkönen Taina, Ilonen Jorma, Knip Mikael

Abstract excerpt

AIM: To determine the association of HLA class II risk with the demographic and clinical characteristics of type 1 diabetes at diagnosis. METHODS: We conducted a register-based retrospective cohort study of 4993 Finnish children (2169 girls) - diagnosed with type 1 diabetes under the age of 15 years in 2003-2016. The participants were divided into six risk groups based on their HLA DR/DQ genotype. Demographic...

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Identifiers

PMID: 36480115
DOI: 10.1111/apa.16621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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