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HLA-typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database.

Pediatric diabetes - 1 Dec 2013

Awa Wendy L, Boehm Bernard O, Rosinger Silke, Achenbach Peter, Ziegler Anette G, Krause Stephanie, Meissner Thomas, Wiegand Susanne, Reinehr Thomas, Kapellen Thomas, Karges Beate, Eiermann Thomas, Schober Edith, Holl Reinhard W

Abstract excerpt

AIM: To characterize the clinical and immunological features of HLA-typed youth with pediatric onset of type 2 diabetes mellitus (T2DM). METHOD: One hundred and seven patients with clinically diagnosed T2DM (aged ≤20 yr at diagnosis) were examined. DNA and serum, obtained after a median diabetes duration of 2.2 (Q1-Q3: 0.8-4.6) yr, were used for centralized HLA-typing and autoantibody (GADA, IA-2A, ZnT8A)...

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PMID: 23627341
DOI: 10.1111/pedi.12043

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