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Heterogeneity in the presentation of clinical type 1 diabetes defined by the level of risk conferred by human leukocyte antigen class II genotypes.

Pediatric diabetes - 1 Mar 2022

Taka Antti-Mathias, Härkönen Taina, Vähäsalo Paula, Lempainen Johanna, Veijola Riitta, Ilonen Jorma, Knip Mikael

Abstract excerpt

OBJECTIVES: The association between human leukocyte antigen (HLA) class II genotypes and susceptibility to type 1 diabetes (T1D) is well established. This study aimed at examining whether there are differences in the presentation of T1D depending on the HLA genotype. RESEARCH DESIGN AND METHODS: We divided the study participants (N = 5798) in the Finnish Pediatric Diabetes Register into two groups based on the...

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PMID: 34894365
DOI: 10.1111/pedi.13300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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