Article
Autoimmune and clinical characteristics of type I diabetes in children with different genetic risk loads defined by HLA-DQB1 alleles. Childhood Diabetes in Finland Study Group.
Clinical science (London, England : 1979) - 1 Mar 1998
Komulainen J, Knip M, Sabbah E, Vähäsalo P, Lounamaa R, Akerblom H K, Reijonen H, Ilonen J
Abstract excerpt
1. The impact of different genetic risk loads defined by HLA-DQB1 alleles on the autoimmune and clinical characteristics of 647 children and adolescents with recent-onset Type I diabetes was evaluated in a prospective population-based study. The subjects were divided into four groups based on HLA...
Topics
- Adolescent
- Alleles
- Autoantibodies
- C-Peptide
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Female
- Follow-Up Studies
- Genotype
- Glutamate Decarboxylase
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans