Article
Gene Deletion of the Kinin Receptor B1 Attenuates Cardiac Inflammation and Fibrosis During the Development of Experimental Diabetic Cardiomyopathy
10 Mar 2009
Abstract excerpt
OBJECTIVE: Diabetic cardiomyopathy is associated with increased mortality in patients with diabetes. The underlying pathology of this disease is still under discussion. We studied the role of the kinin B1 receptor on the development of experimental diabetic cardiomyopathy. RESEARCH DESIGN AND METHODS: We utilized B1 receptor knockout mice and investigated cardiac inflammation, fibrosis, and oxidative stress after...
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