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Article

Multifunctional transcription factor YY1: a therapeutic target in human cancer?

21 Mar 2006

Abstract excerpt

The multifunctional transcription factor Yin Yang 1 (YY1) is a complex protein that has been shown to play pivotal roles in development, differentiation, cellular proliferation and apoptosis. It can act as a transcriptional repressor, an activator, or an initiator element binding protein that directs and initiates transcription of numerous cellular and viral genes. Because the expression and function of YY1 are...

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PMID: 16548774
DOI: 10.1517/14728222.10.2.253

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