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Article

A high-resolution map in the chromosomal region surrounding the Lps locus.

Genomics - 1 Feb 1996

Qureshi S T, Larivière L, Sebastiani G, Clermont S, Skamene E, Gros P, Malo D

Abstract excerpt

The Lps locus on mouse chromosome 4 controls host responsiveness to lipopolysaccharide, a major component of the outer membrane of Gram-negative bacteria. The C3H/HeJ inbred mouse strain is characterized by a mutant Lps allel (Lpsd) that renders it hyporesponsive to LPS and naturally tolerant of its lethal effects. To identify the Lps gene by a positional cloning strategy, we have generated a high-resolution...

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Identifiers

PMID: 8838309
DOI: 10.1006/geno.1996.0050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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