Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinoma

12 Nov 1999

Abstract excerpt

The p16 gene, encodes a key checkpoint protein p16 in the cell cycle, has been reported inactivation in a wide variety of human cancers. We have previously demonstrated high frequency of p16 alterations in primary nasopharyngeal carcinoma (NPC), xenografts and cell lines. The finding implied that inactivation of the p16 gene may play an important role in the NPC development. To investigate the tumour suppressor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10584871
DOI: 10.1038/sj.bjc.6690818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinomaPMID 10584871Read ↗

p16 gene alterations in nasopharyngeal carcinoma.Semantic proximity Read ↗

Role of the p16 tumor suppressor gene in cancer.Semantic proximity Read ↗

The ARF-p16 gene locus in carcinogenesis and therapy of head and neck squamous cell carcinoma.Semantic proximity Read ↗

Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cellsSemantic proximity Read ↗

p16 mutation frequency and clinical correlation in head and neck cancer.Semantic proximity Read ↗

Expression of p16, Rb, and cyclin D1 gene products in oral and laryngeal squamous carcinoma: biological and clinical implications.Semantic proximity Read ↗

p16 gene alterations in locally advanced squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Alterations of the p16 gene in head and neck cancer: frequency and association with p53, PRAD-1 and HPV.Semantic proximity Read ↗

Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma.Semantic proximity Read ↗

p16 overexpression: a potential early indicator of transformation in ovarian carcinoma.Semantic proximity Read ↗

Tumor suppressor gene p16 (CDKN2A) mutation status and promoter inactivation in head and neck cancer.Semantic proximity Read ↗

The Prognostic Relevance of p16 Inactivation in Head and Neck CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.