Genetic analysis of MMP3, MMP9, and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms.

doi:10.1006/bbrc.1999.1721

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Article

Genetic analysis of MMP3, MMP9, and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms.

Biochemical and biophysical research communications - 19 Nov 1999

Yoon S, Tromp G, Vongpunsawad S, Ronkainen A, Juvonen T, Kuivaniemi H

Abstract excerpt

MMP3, MMP9, and PAI-1 are present at increased levels in abdominal aortic aneurysms (AAAs). The promoters of these genes contain polymorphisms, with alleles that exhibit different transcriptional activities in vitro. Association studies were performed using these polymorphisms and DNA isolated from 47 AAA patients, 57 intracranial aneurysm (IA) patients, and 174 controls, all from Finland. PAI-1 and MMP9...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Animals
Aortic Aneurysm, Abdominal
Base Sequence
Case-Control Studies
DNA Primers
Female
Finland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genotype

Humans

Intracranial Aneurysm

Male

Matrix Metalloproteinase 3

Matrix Metalloproteinase 9

Source

Open in PubMed

Identifiers

PMID: 10558909
DOI: 10.1006/bbrc.1999.1721

Genes

MMP3
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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