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Article

ADAMTS genes and the risk of cerebral aneurysm.

Journal of neurosurgery - 1 Aug 2016

Arning Astrid, Jeibmann Astrid, Köhnemann Stephan, Brokinkel Benjamin, Ewelt Christian, Berger Klaus, Wellmann Jürgen, Nowak-Göttl Ulrike, Stummer Walter, Stoll Monika, Holling Markus

Abstract excerpt

OBJECTIVE Cerebral aneurysms (CAs) affect 2%-5% of the population, and familial predisposition plays a significant role in CA pathogenesis. Several lines of evidence suggest that genetic variations in matrix metalloproteinase genes (MMP) are involved in the etiopathology of CAs. The authors performed a case-control study to investigate the effect of 4 MMP variants from the ADAMTS family on the pathogenesis of...

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Source

Identifiers

PMID: 26745484
DOI: 10.3171/2015.7.JNS154

Genes

ADAMTS13
ADAMTS2
ADAMTS12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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