Article
Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains.
Journal of psychiatric research - 1 Sept 2009
Dunham J S, Deakin J F W, Miyajima F, Payton A, Toro C T
Abstract excerpt
Several lines of evidence implicate BDNF in the pathophysiology of psychiatric illness. BDNF polymorphisms have also been associated with the risk of schizophrenia and mood disorders. We therefore investigated whether levels of (pro)BDNF and receptor proteins, TrkB and p75, are altered in hippocampus in schizophrenia and mood disorder and whether polymorphisms in each gene influenced protein expression....
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