Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors.

Development (Cambridge, England) - 1 Dec 1999

Kofron M, Demel T, Xanthos J, Lohr J, Sun B, Sive H, Osada S, Wright C, Wylie C, Heasman J

Abstract excerpt

The maternal transcription factor VegT is important for establishing the primary germ layers in Xenopus. In previous work, we showed that the vegetal masses of embryos lacking maternal VegT do not produce mesoderm-inducing signals and that mesoderm formation in these embryos occurred ectopically, from the vegetal area rather than the equatorial zone of the blastula. Here we have increased the efficiency of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic Induction
Share to Fibroblast Growth Factor 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

Share to Growth Substances

Share to Receptors, Transforming Growth Factor beta

Share to T-Box Domain Proteins

Share to Xenopus Proteins

Share to Zygote

Source

Identifiers

PMID: 10572051
DOI: 10.1242/dev.126.24.5759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors.PMID 10572051Read ↗

The role of maternal VegT in establishing the primary germ layers in Xenopus embryos.Semantic proximity Read ↗

derrière: a TGF-beta family member required for posterior development in Xenopus.Semantic proximity Read ↗

VegT activation of the early zygotic gene Xnr5 requires lifting of Tcf-mediated repression in the Xenopus blastula.Semantic proximity Read ↗

Multiple nodal-related genes act coordinately in Xenopus embryogenesis.Semantic proximity Read ↗

Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.Semantic proximity Read ↗

The eed mutation disrupts anterior mesoderm production in mice.Semantic proximity Read ↗

HNF1(beta) is required for mesoderm induction in the Xenopus embryo.Semantic proximity Read ↗

Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents.Semantic proximity Read ↗

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development.Semantic proximity Read ↗

Multiple signaling pathways control Tbx6 expression during Xenopus myogenesis.Semantic proximity Read ↗

FGF8, Wnt8 and Myf5 are target genes of Tbx6 during anteroposterior specification in Xenopus embryo.Semantic proximity Read ↗

Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.