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Article

HNF1(beta) is required for mesoderm induction in the Xenopus embryo.

Development (Cambridge, England) - 1 Apr 2000

Vignali R, Poggi L, Madeddu F, Barsacchi G

Abstract excerpt

XHNF1(&bgr;) is a homeobox-containing gene initially expressed at the blastula stage in the vegetal part of the Xenopus embryo. We investigated its early role by functional ablation, through mRNA injection of an XHNF1(beta)/engrailed repressor fusion construct (XHNF1(beta)/EngR). Dorsal injections of XHNF1(beta)/EngR mRNA abolish dorsal mesoderm formation, leading to axial deficiencies; ventral injections disrupt...

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Identifiers

PMID: 10704391
DOI: 10.1242/dev.127.7.1455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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