Article
Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.
Development (Cambridge, England) - 15 Sept 2017
Shao Ming, Wang Min, Liu Yuan-Yuan, Ge Yi-Wen, Zhang Yan-Jun, Shi De-Li
Abstract excerpt
The vegetal pole cytoplasm represents a crucial source of maternal dorsal determinants for patterning the dorsoventral axis of the early embryo. Removal of the vegetal yolk in the zebrafish fertilised egg before the completion of the first cleavage results in embryonic ventralisation, but removal of this part at the two-cell stage leads to embryonic dorsalisation. How this is achieved remains unknown. Here, we...
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