The role of maternal VegT in establishing the primary germ layers in Xenopus embryos.

doi:10.1016/s0092-8674(00)81592-5

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Article

The role of maternal VegT in establishing the primary germ layers in Xenopus embryos.

Cell - 21 Aug 1998

Zhang J, Houston D W, King M L, Payne C, Wylie C, Heasman J

Abstract excerpt

VegT is a T-box transcription factor whose mRNA is synthesized during oogenesis and localized in the vegetal hemisphere of the egg and early embryo. We show that maternally expressed VegT controls the pattern of primary germ layer specification in Xenopus embryos. Reduction of the maternal store...

Topics

Animals
Antigens, Differentiation
Body Patterning
DNA-Binding Proteins
Ectoderm
Embryonic Induction
Epidermis
Female
Germ Layers
Mesoderm
Models, Biological
Nervous System
Phenotype
RNA, Messenger
T-Box Domain Proteins
Transcription Factors
Xenopus
Xenopus Proteins

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