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Article

Extensive nucleotide variability within a 370 kb sequence from the central region of the major histocompatibility complex.

Gene - 30 Sept 1999

Gaudieri S, Kulski J K, Dawkins R L, Gojobori T

Abstract excerpt

The recent availability of the genomic sequence spanning the central and telomeric end of the major histocompatibility complex (MHC) has allowed a detailed study of its organisation, gene content and level of nucleotide variability. Previous analyses of nucleotide variability in the MHC have focused on the coding regions of the human leukocyte antigen (HLA) Class I and II genes. Non-coding nucleotide variability...

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PMID: 10570993
DOI: 10.1016/s0378-1119(99)00255-3

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