Article
Notes on individual sequence variation in humans: immunoglobulin kappa light chain.
American journal of human genetics - 1 Jun 1994
Kurth J H, Cavalli-Sforza L L
Abstract excerpt
Little is known concerning the magnitude of variability in the nucleic acid sequence of DNA at the individual level. We have collected a large set of sequence data from the human immunoglobulin kappa light-chain-locus constant region (10,444 bp) and subgroup IV variable region (18,580 bp). For the constant region, absolute conservation of sequence was observed, even in intron and coding-region silent sites, with...
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