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Article

Notes on individual sequence variation in humans: immunoglobulin kappa light chain.

American journal of human genetics - 1 Jun 1994

Kurth J H, Cavalli-Sforza L L

Abstract excerpt

Little is known concerning the magnitude of variability in the nucleic acid sequence of DNA at the individual level. We have collected a large set of sequence data from the human immunoglobulin kappa light-chain-locus constant region (10,444 bp) and subgroup IV variable region (18,580 bp). For the constant region, absolute conservation of sequence was observed, even in intron and coding-region silent sites, with...

Topics

Base Sequence
DNA
Exons
Genes, Immunoglobulin
Genetic Variation
Humans
Immunoglobulin Constant Regions
Immunoglobulin Variable Region
Immunoglobulin kappa-Chains
Introns
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

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Open in PubMed Open full text

Identifiers

PMID: 8198126
PMCID: PMC1918176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8198126-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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