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Article

Aberrant P53 expression lacks prognostic or predictive significance in colorectal cancer: results from the VICTOR trial.

Anticancer research - 1 Mar 2015

McGregor Megan J, Fadhil Wakkas, Wharton Rose, Yanagisawa Yoko, Presz Michael, Pritchard Alison, Womack Chris, Dutton Susan, Kerr Rachel S, Kerr David J, Johnstone Elaine C, Ilyas Mohammad

Abstract excerpt

AIM: Biomarkers with prognostic and predictive value can help stratify patients with colorectal cancer (CRC) into appropriate treatment groups. We sought to evaluate the clinical utility of P53 protein expression as a biomarker in VICTOR, a large phase III trial of rofecoxib in stage II and III CRC. PATIENTS AND METHODS: Tissue micro arrays were constructed from 884 tumors and the expression of P53 was examined...

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PMID: 25750322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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