Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation.

European journal of cancer (Oxford, England : 1990) - 1 Oct 2000

Soong R, Powell B, Elsaleh H, Gnanasampanthan G, Smith D R, Goh H S, Joseph D, Iacopetta B

Abstract excerpt

Previous studies on the prognostic significance of TP53 gene alterations in colorectal cancer (CRC) have led to conflicting results. The present study investigated the prognostic significance of TP53 gene mutation in a very large series of 995 Dukes' B and C CRC patients, the majority of whom did...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Antineoplastic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemotherapy, Adjuvant

Share to Colorectal Neoplasms

Share to Genes, p53

Share to Logistic Models

Share to Prognosis

Source

Identifiers

PMID: 11044641
DOI: 10.1016/s0959-8049(00)00285-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11044641-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation.PMID 11044641Read ↗

The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment.Semantic proximity Read ↗

The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

Mutations in TP53 are a prognostic factor in colorectal hepatic metastases undergoing surgical resection.Semantic proximity Read ↗

Aberrant P53 expression lacks prognostic or predictive significance in colorectal cancer: results from the VICTOR trial.Semantic proximity Read ↗

Functional TP53 mutations have no impact on response to cytotoxic agents in metastatic colon cancer.Semantic proximity Read ↗

Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: a p53 Research Group study.Semantic proximity Read ↗

TP53 mutation in colorectal cancer.Semantic proximity Read ↗

TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.Semantic proximity Read ↗

TP53 mutations in advanced colorectal cancer: the dark side of the moon.Semantic proximity Read ↗

Prognostic significance of p53 mutations in colon cancer at the population level.Semantic proximity Read ↗

Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies.Semantic proximity Read ↗

P53 alterations have no prognostic or predictive significance in Dukes' C rectal carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.