Article
Patterns of chromosomal imbalances in invasive breast cancer.
International journal of cancer - 20 May 2000
Richard F, Pacyna-Gengelbach M, Schlüns K, Fleige B, Winzer K J, Szymas J, Dietel M, Petersen I, Schwendel A
Abstract excerpt
Invasive breast carcinomas are characterized by a complex pattern of chromosomal alterations. We applied comparative genomic hybridization (CGH) to analyze 105 primary breast carcinomas using histograms to indicate the incidence of DNA imbalances of tumor subgroups and difference histograms to compare invasive ductal carcinomas (IDC) with lobular carcinomas (ILC), well and poorly differentiated carcinomas (G1/G3)...
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