Article
Effects of serotonin transporter promoter genotype on platelet serotonin transporter functionality in depressed children and adolescents.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Nov 1999
Nobile M, Begni B, Giorda R, Frigerio A, Marino C, Molteni M, Ferrarese C, Battaglia M
Abstract excerpt
OBJECTIVE: To investigate possible associations between serotonin transporter (5-HTT) promoter genotypic variants (l/l, l/s, and s/s) and differential regulation of platelet 5-HTT functionality parameters in a group of drug-naive depressed children and adolescents and healthy controls. METHOD: Children and adolescents with major depression (n = 18) defined by DSM-III-R criteria and normal controls (n = 21) were...
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