Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.

Nucleic acids research - 1 Dec 1999

Kressler D, Rojo M, Linder P, Cruz J

Abstract excerpt

Several mutants ( spb1 - spb7 ) have been previously identified as cold-sensitive extragenic suppressors of loss-of-function mutations in the poly(A)(+)-binding protein 1 of Saccharomyces cerevisiae. Cloning, sequence and disruption analyses revealed that SPB1 (YCL054W) encodes an essential putative S -adenosylmethionine-dependent methyltransferase. Polysome analyses showed an under-accumulation of 60S ribosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to DNA Modification Methylases
Share to Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methyltransferases

Share to Ribosomes

Share to RNA Precursors

Share to RNA Processing, Post-Transcriptional

Share to RNA, Ribosomal

Source

Open in PubMed Open full text

Identifiers

PMID: 10556316
DOI: 10.1093/nar/27.23.4598
PMCID: PMC148748

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.PMID 10556316Read ↗

Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.Semantic proximity Read ↗

Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae.Semantic proximity Read ↗

Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.Semantic proximity Read ↗

Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46.Semantic proximity Read ↗

DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiae.Semantic proximity Read ↗

Loc1p is required for efficient assembly and nuclear export of the 60S ribosomal subunit.Semantic proximity Read ↗

Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation, and ribosome assembly.Semantic proximity Read ↗

Synthetic lethality with conditional dbp6 alleles identifies rsa1p, a nucleoplasmic protein involved in the assembly of 60S ribosomal subunits.Semantic proximity Read ↗

Rbs1, a new protein implicated in RNA polymerase III biogenesis in yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Has1p, a member of the DEAD-box family, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.