Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46.

doi:10.1126/science.2408148

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Article

Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46.

Science (New York, N.Y.) - 2 Mar 1990

Sachs A B, Davis R W

Abstract excerpt

Cold-sensitive mutations in the SPB genes (spb1-spb7) of Saccharomyces cerevisiae suppress the inhibition of translation initiation resulting from deletion of the poly(A)-binding protein gene (PAB1). The SPB4 protein belongs to a family of adenosine triphosphate (ATP)-dependent RNA helicases. The...

Topics

Amino Acid Sequence
Base Sequence
Carrier Proteins
DEAD-box RNA Helicases
Molecular Sequence Data
Mutation
Poly(A)-Binding Proteins
Protein Biosynthesis
RNA Nucleotidyltransferases
RNA Processing, Post-Transcriptional
RNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal

Ribosomal Proteins

Ribosomes

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 2408148
DOI: 10.1126/science.2408148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2408148-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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