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Article

Synthetic lethality with conditional dbp6 alleles identifies rsa1p, a nucleoplasmic protein involved in the assembly of 60S ribosomal subunits.

Molecular and cellular biology - 1 Dec 1999

Kressler D, Doère M, Rojo M, Linder P

Abstract excerpt

Dbp6p is an essential putative ATP-dependent RNA helicase that is required for 60S-ribosomal-subunit assembly in the yeast Saccharomyces cerevisiae (D. Kressler, J. de la Cruz, M. Rojo, and P. Linder, Mol. Cell. Biol. 18:1855-1865, 1998). To identify factors that are functionally interacting with Dbp6p, we have performed a synthetic lethal screen with conditional dbp6 mutants. Here, we describe the cloning and...

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Identifiers

PMID: 10567587
DOI: 10.1128/MCB.19.12.8633
PMCID: PMC85000

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