Article
IL-13 supports differentiation of dendritic cells from circulating precursors in concert with GM-CSF.
European cytokine network - 1 Jan 2000
Piemonti L, Bernasconi S, Luini W, Trobonjaca Z, Minty A, Allavena P, Mantovani A
Abstract excerpt
Dendritic cells (DC) can be obtained from peripheral blood mononuclear cells (PBMC) by in vitro culture with IL-4 and granulocyte-macrophage colony-stimulating factor (GM-CSF). IL-13 shares properties with IL-4 but its receptor does not involve the common gamma chain present in the receptor compl...
Topics
- Antigens, Differentiation
- Cell Differentiation
- Dendritic Cells
- Drug Interactions
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- In Vitro Techniques
- Interleukin-13
- Interleukin-4
- Leukapheresis
- Lymphocyte Culture Test, Mixed
